Angel Medical was founded by Dr. Robert E. Fischell and Dr. David R. Fischell. The AngelMed Guardian® system is an implantable cardiac device, designed to detect rapid ST segment shifts that may signify major cardiac events, such as coronary artery occlusions caused by life-threatening vulnerable plaque ruptures. Once an ST shift is detected, the system is designed to alert patients to seek medical care by delivering a series of vibratory, auditory, and visual warnings. The AngelMed Guardian system is intended to address the challenge of patients not recognizing nor responding quickly to heart attacks. Continue reading
Brainsgate‘s implantable pulse generator is designed to stimulate the Spheno-Palatine Ganglion. It is activated by an external transcutaneous energy transmitter. Brainsgate is evaluating the system’s capability to augment cerebral blood flow as a treatment of ischemic stroke or dementia. Continue reading
Yossi Gross (born February 5, 1947) is an Israeli medical device innovator and entrepreneur. His medical-device companies are incubated through Rainbow Medical.
Currently, the following companies led by Yossi Gross are focusing on active implantable medical devices:
- BetaStim, developing a new neurostimulation treatment for diabetes
- Brainsgate, developing an implantable device for acute stroke treatment and brain drug-delivery technology
- BioControl Medical, developing neurostimulation devices
- Enopace Biomedical, developing implantable devices for heart failure treatment through stimulation of the aorta
- CerebralRx, a spin-off from Biocontrol developing vagus nerve stimulators for the treatment of epilepsy
Dr. Shlomo Ben-Haim has held faculty appointments as a Professor of Medicine, Physiology and Biophysics, at both Harvard University and the Technion – Israel Institute of Technology. His formal education is in the fields of nuclear physics, mathematics, biomedical engineering, philosophy, and medicine. Dr. Ben-Haim has published his research in over 100 scientific papers, in peer-reviewed journals. He holds over 180 patents and patent applications.
Currently, two companies led by Dr. Ben-Haim are focusing on active implantable medical devices:
Mir A. Imran (born 1956, Hyderabad, India), is an Indian entrepreneur and venture capitalist. Imran has formed 19 companies since the early 80s and holds over 140 patents. He is the founder and Chairman of InCube Laboratories, Inc., a research laboratory and business incubator for medical and technology companies
Currently, four InCube companies are focusing on active implantable medical devices:
- Intrapace, which is developing an implantable device to treat obesity
- Spinal Modulation, which is developing a novel therapy for the management of chronic pain with an implantable microstimulator
- Neurolink, which is developing a novel therapy for epilepsy
- Corhythm, which is focused on the treatment of AFIB
Spinal Modulation is a company based in Menlo Park, CA. It has developed a neurostimulator for chronic intractable pain management.
According to the company, the Spinal Modulation System utilizes low-level electrical signals to modulate neural structures of primary sensory neurons located within the dorsal root ganglion (DRG). These cell bodies have been implicated in the development and maintenance of chronic pain conditions. Continue reading