A blog about what is new (and old) in the world of active implantable medical devices 

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SMSI® Implantable Glucose Sensor

SMSI implantable glucose sensor Sensors for Medicine and Science, Inc. (SMSI)  of Germantown, MD was founded in 1997 to develop chemical sensing technologies based on fluorescence sensing.

SMSI® is now developing an implantable glucose sensor that is designed to automatically measure interstitial glucose every few minutes. The sensor implant communicates wirelessly with a small external reader, allowing it to track the rate of change of glucose levels and warn the user of impending hypo- or hyperglycemia. According to SMSI, the target operational life of the sensor implant will be 6-12 months, after which it would be replaced.

"wrist watch" style receiver for SMSI implantable glucose sensorSMSI’s sensor operates on induced fluorescence changes.  The most interesting characteristic of SMSI’s approach is that neither the indicator nor analyte are consumed – The fluorescent indicator molecule and the analyte interact directly yet reversibly. This is in stark contrast to commercialized glucose sensors, which need a continuous supply of fresh glucose, as well as reagents/strips.

The implantable device consists of a bean-shaped waveguide, encapsulated in the indicator matrix, and combined with telemetry capabilities.

In October 2011 SMSI announced that it received $54.1 million in fourth round funding for product development and regulatory approvals.

Company website: www.s4ms.com

 

 

 

 

 
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