A curious device spotted at the 2019 MD&M West was the C-MIC from Berlin Heals GmbH – a private company based in Berlin, Germany.
Berlin Heals is developing an implantable electroceutical device (C-MIC) intended to readjust the disturbed myocardial electrical gradient that, according to Berlin Heals, occurs in heart failure patients. According to the company, preclinical trials have confirmed that failing hearts with an extremely remodeled myocardium show reverse remodeling with normalized heart function after a short treatment period using a DC electrical gradient applied to the myocardium.
The latest publication on the company’s technology is “Bioelectrical signals improve cardiac function and modify gene expression of extracellular matrix components”, ESC Heart Failure 2017; 4: 291–300. It is available online at https://onlinelibrary.wiley.com/doi/epdf/10.1002/ehf2.12169 An animation of the proposed therapy is available at: http://berlinheals.de/what-we-do/
Berlin Heals website: http://berlinheals.de/