A blog about what is new (and old) in the world of active implantable medical devices 

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Medtronic’s Chronicle Implantable Hemodynamic Monitor for Heart Failure Monitoring

Image Credit: Medtronic The Medtronic Chronicle implantable hemodynamic monitor used a specialized RV lead/sensor.  The device was able to monitor and telemeter: Systolic and diastolic pressure Estimated pulmonary artery diastolic pressure RV dp/dt (positive & negative) Heart rate & activity Core body temperature Continuous remote monitoring

 
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Medcor Corporation’s Pacemakers (ca. 1975)

Medcor was established in Hollywood, FL in 1969, and began developing pacemakers, lead and accessories in 1971.  By 1975 it had a series of lithium-powered pacemaker in the market, but they never became popular with physicians. On July 1980, Daig Corporation of Minnetonka, MN acquired Medcor with the expectation that Medcor pacemaker technology could be profitably marketed. Daig had

 
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VeriMed’s Human-Implantable VeriChip Patient RFID

VeriMed’s VeriChip is the only RFID tag that has been cleared by FDA for human implant.  The concept behind the medical use of the VeriChip is that patients would have the tiny chip implanted just under the skin, in the back of the arm.  Each VeriMed microchip contains a unique identification number that emergency personnel may scan to

 
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CardioMEMS Miniature Implantable Wireless Sensors

CardioMEMS was founded by Dr. Jay S. Yadav and Dr. Mark G. Allen in Atlanta, GA in 2000 to develop implantable micro-electromechanical sensors to improve the management of severe chronic cardiovascular diseases such as heart failure and aneurysms. The miniature wireless sensors can be delivered through a catheter.  Once in place, they transmit cardiac output, blood

 
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NDI Medical’s Miniature MicroPulse Neurostimulator

Image Credit: SPR Therapeutics NDI Medical was founded in 2002 by Geoffrey B. Thrope to develop and commercialize neurodevice products.  NDI Medical developed the MicroPulse neurostimulator, a thumb-sized, rechargeable pulse generator, that has been used for the treatment of incontinence and pain, as well as an implantable device for the restoration of function of paralyzed limbs. According to a 2006

 
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Leptos Biomedical’s Splanchnic Nerve Stimulation For Treatment Of Obesity (2002-2010)

Leptos Biomedical was founded in Fridley, MN in 2002 by Dr. John D. Dobak.   Leptos intended to develop an implantable device to stimulate the greater splanchnic nerve, that was hoped would  result in reduced food intake and increased energy expenditure. In February 2010 Leptos announced its closure.  Reasons were not provided, but it has been suggested that the decision

 
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Palyon Medical’s Implantable Programmable Pain-Medicine Pump

  Image Credit: Palyon Medical’s animation at www.biodigital.com Palyon Medical Corporation was founded in 2004 in New York, NY, but recently moved its operations to Santa Clarita, CA.  Palyon is still operating stealthily. Palyon is developing a programmable implantable drug delivery system (IDDS) which delivers targeted doses of pain medication directly to the spinal area for the

 
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Neuros Medical’s Implantable Device to Alleviate Amputation Pain

Image Credit: Neuros Medical Neuros Medical was founded by Jon J. Snyder in Cleveland, OH in 2008 to develop a neurostimulation therapy to alleviate chronic pain.  The company’s Electrical Nerve Block™ technology is based on research done at Case Western Reserve University. The company’s Nerve Block is an implantable device that delivers high-frequency stimulation to sensory nerves in the

 
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Reliability Analysis of Active Implantable Medical Devices

We conduct reliability analyses for our implantable devices on a continued basis.  I’ve spent the last few days readying the data for this period’s analysis, and thought that  a short primer on how this is actually done would be of interest to fellow engineers who may need it at some point. You surely have heard

 
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NeuroVista’s Implantable EEG for Seizure Prediction

Seattle-based NeuroVista was founded in 2002 by Dr. Daniel DiLorenzo to develop an implantable device for the early detection of epileptic seizures. The NeuroVista seizure advisory system is based on an implantable device that senses EEG irregularities that precede a seizure. Early warning allows patients to take medicine and find a safe place to lie down. Although some

 
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Radiation-Hardened ICs for Implantable Medical Devices

Lately I’ve received many inquiries about the paper on radiation-hardness testing of implantable integrated circuits that I published with Dr. Larry Stotts (now Executive VP R&D at Biotronik), and the late Dr. John Prince.  This is because the effects of medical diagnostic and therapeutic radiation are becoming an issue of concern to physicians who often encounter

 
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InControl’s Metrix Atrioverter (1990-1998)

 InControl was founded in 1990 in Redmond, WA to develop an implantable device for treating atrial fibrillation.  In November 1995, InControl announced the first human implant of its Metrix atrioverter. The implantable atrioverter system consisted of an implantable atrial defibrillator (model 3000 or 3020) connected to right atrial (perimeter right atrial model 7205) and coronary sinus (perimeter coronary sinus model 7109)

 
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Cactus/Freescale Semiconductor ICs for Implantable Medical Devices

Image Credit: Freescale Semiconductor, from “Integrated Circuits for Implantable Medical Devices”  An article by Steve Taranovich in the December 15, 2011 issue of EDN discussed technologies that are expected to be hot in 2012. One of these is the implantable chipset being developed by a collaborative effort between Cactus Semiconductor of Chandler, AZ and semiconductor giant

 
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Victhom Human Bionics’ Neurostep Implantable Closed-Loop Stimulator for Foot Drop

Image Credit: Victhom Human Bionics Victhom Human Bionics was founded in 2002 in Saint-Augustin-de-Desmaures, Canada. The company’s Neurobionix business unit develops its implantable closed-loop system devices. The Neurostep® is a neurostimulator designed to be implanted into the patient’s leg. Electrodes are attached to the peripheral nerves responsible for sensing and stimulating the muscles that lift

 
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Spinal Modulation’s Neurostimulator for the Stimulation of the Dorsal Root Ganglion

Image Credit: Spinal Modulation   Spinal Modulation was founded by Mir Imran in Menlo Park, CA in 2004.  The company has developed an implantable neurostimulator to deliver signals to the primary sensory neurons located within the dorsal root ganglion (DRG).  The idea is that unlike dorsal column spinal cord stimulation, the Spinal Modulation system breaks the

 
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