Cyberonics was founded in Houston, TX in 1987 to develop an implantable device for the treatment of epilepsy. In July 1997, The FDA approved the VNS Therapy System (formerly known as the NCP® NeuroCybernetic Prosthesis System) as an adjunctive epilepsy treatment for adults and children over 12 years of age with partial onset seizures refractory to
Respicardia, Inc. (formerly Cardiac Concepts, Inc.) is a privately held medical device company incorporated in 2006. It is located in Minneapolis, Minnesota, USA. It is developing an implantable system intended to improve the outcomes for Heart Failure patients by developing an implantable stimulation therapy to treat Central Sleep Apnea. The remedē System is an implantable
The aura6000 is based on ImThera’s Targeted Hypoglossal Neurostimulation (THN) Sleep Therapy™ delivering neurostimulation to the tongue during sleep. The system is comprised of a surgically‐placed multi‐contact electrode specifically designed for the Hypoglossal nerve, and a lead that connects the electrode to a programmable implantable pulse generator (IPG) that is placed in the anterior chest wall.
MedicalApnex Medical, Inc. is located in St. Paul, MN. It was founded in 2006 and has developed the Hypoglossal Nerve Stimulation System (HGNS® System) for the treatment of obstructive sleep apnea (OSA). The HGNS System has been evaluated in feasibility studies and is now being assessed in an Investigational Device Exemption (IDE) Study (Apnex®Clinical Study).
Inspire Medical Systems, based in Minneapolis, Minnesota, develops implantable neurostimulation systems to treat Obstructive Sleep Apnea (OSA). Inspire Medical Systems was formed when the Inspire intellectual property and technology was licensed and spun out from Medtronic in 2007. Inspire therapy is designed to deliver physiologically-timed, mild stimulation to the hypoglossal nerve on each breathing cycle
Angel Medical was founded by Dr. Robert E. Fischell and Dr. David R. Fischell. The AngelMed Guardian® system is an implantable cardiac device, designed to detect rapid ST segment shifts that may signify major cardiac events, such as coronary artery occlusions caused by life-threatening vulnerable plaque ruptures. Once an ST shift is detected, the system
Brainsgate‘s implantable pulse generator is designed to stimulate the Spheno-Palatine Ganglion. It is activated by an external transcutaneous energy transmitter. Brainsgate is evaluating the system’s capability to augment cerebral blood flow as a treatment of ischemic stroke or dementia.
Yossi Gross (born February 5, 1947) is an Israeli medical device innovator and entrepreneur. His medical-device companies are incubated through Rainbow Medical. Currently, the following companies led by Yossi Gross are focusing on active implantable medical devices: BetaStim, developing a new neurostimulation treatment for diabetes Brainsgate, developing an implantable device for acute stroke treatment and brain
Spinal Modulation is a company based in Menlo Park, CA. It has developed a neurostimulator for chronic intractable pain management. According to the company, the Spinal Modulation System utilizes low-level electrical signals to modulate neural structures of primary sensory neurons located within the dorsal root ganglion (DRG). These cell bodies have been implicated in the
Morgan Technical Ceramics (MTC) announced that its Bedford, Ohio site manufactures the piezoelectric ceramic materials used in EBR Systems, Inc.’s innovative new WiCS® Wireless Cardiac Stimulation System. The PZT (lead zirconate titanate) material made by MTC is critical to the efficiency of the WiCS system, which is powered by a battery with a 10-year lifespan.
The November issue of Evaluation Engineering carried an article by Tom Lecklider on the amount of work invested by Medtronic to develop and test the Revo MRI pacemaker system. The article is available on-line at Evaluation Engineering (Click here for direct link to the November 2011 issue).
Intermedics’ next-generation pacing platform would have been full of neat features such as: hemodynamic sensing (impedance-based hemodynamic sensor), autocapture (capture verification), autothreshold (self-tuning based on automatic strength-duration curve generation), high-quality digital telemetry, large-volume memory for electrogram storage, non-volatile memory for self-recovery and patient information, advanced noise detection, etc. My favorite feature though was “Patient Alert”.