A blog about what is new (and old) in the world of active implantable medical devices 

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Home Archive for category "Treated Conditions" (Page 8)
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American Optical Cardio-Care Demand Pacemaker (1968)

Barouh Berkovits at American Optical Co of Boston, MA designed the first “Demand Pacemaker” – what we now know as a VVI pacemaker. The Cardio-Care Demand Pacemaker, introduced in 1968, was American Optical’s first implantable device. From Kirk Jeffrey’s Machines in our Hearts(2001): “Berkovits in 1963 designed a sensing capability into the pacemaker. His invention behaved exactly like an

 
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A Challenge to History Buffs: Who Was Digikon?

I took this picture a very long time ago at the office of one of my implanter friends in Europe.  Ever since then, I’ve tried to find out about “Digikon,” but have had no luck so far.  All that I have been able to find from the St. Jude legacy device database is that Digikon had produced

 
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Cook Pacemaker’s Sensor Kelvin 504 Central-Venous-Temperature-Sensing Pacemaker (ca. 1992)

In 1983, Bill Cook and Dr. Neal Fearnot began to work under the Cook Pacemaker Company in Leechburg, PA on developing the technology developed by Dr. Fearnot at Purdue University into an improved prototype for a temperature-based exercise responsive pacemaker that was released in 1988 as the Kelvin Sensor rate-responsive pacemaker.  One of the first CVT

 
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Intermedics’ Circadia Central Venous Temperature-Sensing Pacemaker (ca. 1993)

The Circadia pacemaker was one of the very few devices that had a lead-borne thermistor to measure cental venous temperature (CVT) as a sensor for rate-response. A unique feature of this pacemaker was an iridium-oxide (IrOx)-coated button welded to the can.  It was believed that this button would improve unipolar IEGM sensing and reduce unipolar

 
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Cook’s Sensor Kelvin and Intermedics’ Circadia Temperature-Sensing Rate-Responsive Pacemakers

  One of the indicators of metabolic demand that has been used for controlling the rate of pacemakers is central venous blood temperature (CVT). In 1983, Bill Cook and Dr. Neal Fearnot began to work under the Cook Pacemaker Company on developing the technology developed by Dr. Fearnot at Purdue University into an improved prototype for

 
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Medtronic’s Chronicle Implantable Hemodynamic Monitor for Heart Failure Monitoring

Image Credit: Medtronic The Medtronic Chronicle implantable hemodynamic monitor used a specialized RV lead/sensor.  The device was able to monitor and telemeter: Systolic and diastolic pressure Estimated pulmonary artery diastolic pressure RV dp/dt (positive & negative) Heart rate & activity Core body temperature Continuous remote monitoring

 
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Medcor Corporation’s Pacemakers (ca. 1975)

Medcor was established in Hollywood, FL in 1969, and began developing pacemakers, lead and accessories in 1971.  By 1975 it had a series of lithium-powered pacemaker in the market, but they never became popular with physicians. On July 1980, Daig Corporation of Minnetonka, MN acquired Medcor with the expectation that Medcor pacemaker technology could be profitably marketed. Daig had

 
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VeriMed’s Human-Implantable VeriChip Patient RFID

VeriMed’s VeriChip is the only RFID tag that has been cleared by FDA for human implant.  The concept behind the medical use of the VeriChip is that patients would have the tiny chip implanted just under the skin, in the back of the arm.  Each VeriMed microchip contains a unique identification number that emergency personnel may scan to

 
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CardioMEMS Miniature Implantable Wireless Sensors

CardioMEMS was founded by Dr. Jay S. Yadav and Dr. Mark G. Allen in Atlanta, GA in 2000 to develop implantable micro-electromechanical sensors to improve the management of severe chronic cardiovascular diseases such as heart failure and aneurysms. The miniature wireless sensors can be delivered through a catheter.  Once in place, they transmit cardiac output, blood

 
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NDI Medical’s Miniature MicroPulse Neurostimulator

Image Credit: SPR Therapeutics NDI Medical was founded in 2002 by Geoffrey B. Thrope to develop and commercialize neurodevice products.  NDI Medical developed the MicroPulse neurostimulator, a thumb-sized, rechargeable pulse generator, that has been used for the treatment of incontinence and pain, as well as an implantable device for the restoration of function of paralyzed limbs. According to a 2006

 
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Leptos Biomedical’s Splanchnic Nerve Stimulation For Treatment Of Obesity (2002-2010)

Leptos Biomedical was founded in Fridley, MN in 2002 by Dr. John D. Dobak.   Leptos intended to develop an implantable device to stimulate the greater splanchnic nerve, that was hoped would  result in reduced food intake and increased energy expenditure. In February 2010 Leptos announced its closure.  Reasons were not provided, but it has been suggested that the decision

 
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Palyon Medical’s Implantable Programmable Pain-Medicine Pump

  Image Credit: Palyon Medical’s animation at www.biodigital.com Palyon Medical Corporation was founded in 2004 in New York, NY, but recently moved its operations to Santa Clarita, CA.  Palyon is still operating stealthily. Palyon is developing a programmable implantable drug delivery system (IDDS) which delivers targeted doses of pain medication directly to the spinal area for the

 
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Neuros Medical’s Implantable Device to Alleviate Amputation Pain

Image Credit: Neuros Medical Neuros Medical was founded by Jon J. Snyder in Cleveland, OH in 2008 to develop a neurostimulation therapy to alleviate chronic pain.  The company’s Electrical Nerve Block™ technology is based on research done at Case Western Reserve University. The company’s Nerve Block is an implantable device that delivers high-frequency stimulation to sensory nerves in the

 
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NeuroVista’s Implantable EEG for Seizure Prediction

Seattle-based NeuroVista was founded in 2002 by Dr. Daniel DiLorenzo to develop an implantable device for the early detection of epileptic seizures. The NeuroVista seizure advisory system is based on an implantable device that senses EEG irregularities that precede a seizure. Early warning allows patients to take medicine and find a safe place to lie down. Although some

 
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Radiation-Hardened ICs for Implantable Medical Devices

Lately I’ve received many inquiries about the paper on radiation-hardness testing of implantable integrated circuits that I published with Dr. Larry Stotts (now Executive VP R&D at Biotronik), and the late Dr. John Prince.  This is because the effects of medical diagnostic and therapeutic radiation are becoming an issue of concern to physicians who often encounter

 
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