A blog about what is new (and old) in the world of active implantable medical devices 

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Home Archive for category "Therapies" (Page 10)
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BioControl’s MiniatURO Muscle Stimulator to Alleviate Incontinence (1999-2006)

BioControl Medical, Ltd. was founded in 1999 by Yossi Gross, and is based in Yehud, Israel.  BioControl’s first devices were developed to treat incontinence due to overactive bladder, stress, and interstitial cystitis.  In 2006 American Medical Sytems acquired an exclusive license for the use of the technology in urology, gynaecology and other pelvic health applications. The BioControl MiniatURO

 
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BioControl’s CardioFit System for the Treatment of Heart Failure via Vagus Nerve Stimulation

BioControl Medical, Ltd. was founded in 1999 by Yossi Gross, and is based in Yehud, Israel.  BioControl’s first devices were developed to treat incontinence due to overactive bladder, stress, and interstitial cystitis.  In 2006 American Medical Sytems acquired an exclusive license for the use of the technology in urology, gynecology and other pelvic health applications.

 
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Cameron Health’s Leadless Implantable Defibrillator

Cameron Health was founded in 2000 in San Clemente, CA to develop a leadless implantable defibrillator. The device does not require a lead to be implanted into the heart. Instead, the device has a lead that is tunneled beneath the skin from the upper left chest below the level of the clavicle to the level of about

 
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Medtronic’s Leadless Pacemakers

Medtronic announced at TEDMED 2010 that it is working on leadless pacemakers.  Dr. Stephen Osterle, senior vice president of medicine and technology and member of Medtronic’s Executive Management Team, unveiled the device. Osterle said that physicians will be able to control the device with a smart phone.

 
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EBR System’s Wireless Pacemaker

EBR Systems, Inc., founded in 2003 and headquartered in Sunnyvale, CA, is developing the WiCS® Wireless Cardiac Stimulation technology to eliminate cardiac pacing leads, historically a major source of complications and reliability issues.  The startup was spun out of research by founder Debra Echt, a former professor of medicine and a cardiologist at Vanderbilt University.

 
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Nanostim’s Leadless Pacemaker

Nanostim is an early-stage AIMD company in Milpitas, CA that is developing a pacemaker that can be implanted inside the heart through a catheter.  The tiny device is attached directly to the heart, eliminating the need for leads. In May 2011 Nanostim announced that St. Jude Medical had made a substantial investment in the company. The company is operating in

 
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American Optical’s Nuclear Pacemaker (1970’s)

Barouh Berkovits at American Optical Co of Boston, MA designed the first “Demand Pacemaker” – what we now know as a VVI pacemaker.  As other companies in the 1970s, American Optical developed a nuclear-battery-powered version of their pacemaker. American Optical used a 3Ci Pu-238 Radioisotope Thermal Generator (RTG) produced by Fred Hittman’s Hittman Nuclear Development Corp. (Model NB-200).  It consisted of a tiny 8 Ci

 
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Arco Medical’s Nuclear-Powered Pacemaker (ca.1974)

An isotopic thermoelectric generator was developed in the US by Numec Corporation under a contract from the US Atomic Energy Commission and sold for $3,200 (back in 1974). The thermopile consisted of doped bismuth telluride pairs that were placed in a parallel/series arrangement to generate some 300 μW of power to run this Arco Medical

 
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Medtronic’s Atomic Pacemaker (early 1970’s)

In the late 1960s Medtronic – today the largest manufacturer of implantable medical devices in the world – teamed up with Alcatel, a French company, to design a nuclear-powered pacemaker. The first human implant of the device took place in Paris in 1970. The nuclear battery in the Medtronic device used a tiny 2.5 Ci

 
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CCC del Uruguay’s Atomic Pacemaker (1972)

This nuclear pacemaker was manufactured ca. 1972 by Dr. Orestes Fiandra’s CCC del Uruguay. It was powered by a McDonell-Douglas Betacel 400 which had promethium-147 sandwiched between semiconductor wafers. As the radioactive promethium isotope decays, it emits β-particles (electrons). The impact of the β-particles on a p-n junction causes a forward bias in the semiconductor

 
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Indian Pacemaker Companies: Shree Pacetronix and MediVed

Shree Pacetronix Ltd., was founded in Pithampur, Dist. Dhar, India in 1988.  In 1993 the company was converted to a Public Limited Company. The company is listed on the Bombay Stock Exchange and regional exchanges. Pacetronix’s website shows EC type certificates for its Pinnacle SSIR (model 297), Pinnacle SSI (model 8820), Charak DDD (model ND 747), and Akash VDD (model

 
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CCC del Uruguay’s Early Mercury-Cell Pacemaker (1969)

This is one of my most prized possessions.  It is one of the very first pacemakers produced by CCC del Uruguay in 1969.  It was given to me by my friend, the late Dr. Orestes Fiandra, founder of CCC del Uruguay. On February 2, 1960, Dr. Orestes Fiandra and Dr. Roberto Rubio accomplished the first succesful long-term

 
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CCC Medical – Top OEM to AIMD Start-Ups

CCC is one of the oldest pacemaker manufacturers in the world. It was founded in 1969 by Dr. Orestes Fiandra, who performed the first succesful, human, long-term pacemaker implant in the world. This was achieved in Uruguay on February 2, 1960 by Dr. Orestes Fiandra and Dr. Roberto Rubio. The pacemaker was manufactured by Dr. Rune Elmqvist of

 
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Omikron Scientific – Israeli Pacemaker Company (1979-1985)

Omikron Scientific was a small-scale pacemaker company founded in Rehovot, Israel in 1979.  The company stopped pacemaker production in 1985. Besides pacemakers, Omikron also produced a skin substitute called Omniderm, which was a thin, transparent, flexible membrane. It was used when a biological dressing would otherwise have been used. Omikron’s pacemakers were all VVI and featured gradual decline Magnet Rate

 
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MicroTransponder’s Injectable Stimulators

    MicroTransponder was founded in Dallas, TX in  2007 when it licensed technology developed at University of Texas in Dallas (UTD) by Larry Cauller, who heads the cortical connections lab. The first wireless transponder was developed under a DARPA Revolutionizing Prosthetics grant to create a bi-directional neural interface for a prosthetic hand.

 
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